Edmond H. Fischer and Edwin G. Krebs receive the Nobel Prize for Medicine on October 12, 1992.

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On October 12, 1992, Edmond H. Fischer (b. 1920) and Edwin G. Krebs (b. 1918) of the University of Washington School of Medicine receive the Nobel Prize for Medicine for their discoveries in the 1950s concerning "reversible protein phosphorylation." Scientists worldwide have drawn on the work for a vast spectrum of research on cellular processes. They share the $1.2 million prize.

Krebs was a professor in Pharmacology and Biochemistry and Fischer was a professor in Biochemistry. Their work helped researchers better understand such things as diabetes; how the rejection of transplanted organs is prevented; Alzheimer's disease; why certain cancers develop; and how the body mobilizes sugar to produce energy.

The Nobel Prize was established in the will of Alfred Nobel (1833-1896) for annual awards to men and women who confer the greatest benefit on humankind in the fields of physics, chemistry, physiology or medicine, literature, and peace.

Sources:
Rebecca Hughes, "After The Prize," Columns, March 1998, (http://www.washington.edu /alumni/ columns/index.html); "Two Scientists At UW Win Nobel For Medicine," The Seattle Times, October 12, 1992, p. A-1.

By David Wilma, December 27, 2001

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Edmond H. Fischer (b. 1920), 1992
Courtesy University of Washington

Edwin G. Krebs (b. 1918), 1992
Courtesy University of Washington